Hi

Easiest to avoid such issues is to open the result in a new tab, that allows to close the tab to go back to the Firefox Home page.

You can hold down the left mouse button on the back button or right-click to open the tab history to see if you can find the Firefox Home entry.

I can tell that I will not be able to navigate back to Firefox Home Page because once I hit enter key after typing my search terms and get to the next page to see search result, the back button is still greyed out.

This is a very recent change. In fact, if I launch a clean profile, I can see that the behaviour there is as I expect. So why is it that Firefox settings get to mess up on their own and the only solution is to refresh thereby losing all the settings.

This is one thing that is very frustrating about Firefox. Settings keep changing and there's nothing to be done other than refreshing. I can definitely understand why Firefox market share is so low. Searching the web I see so many issues are resolved by refreshing Firefox yet none of the other browser have such drastic measure of correcting issues. If it wasn't the power of containers, I'd have already left Firefox. I guess we have to keep dealing with such.

I'm beyond frustrated and now I'm starting to ramble on. I'll leave it at that.

You mention containers in your above reply. If you use containers then that could be a possible cause for this permission issue.